Ácido poli-l-láctico para rejuvenescimento facial na prática em consultório

RESUMO

A cada dia que envelhecemos, nossa pele se torna mais fina, desidratada e frágil. Flacidez, rugas e manchas de idade começam a surgir. O rejuvenescimento facial na Odontologia é uma área de atuação relativamente nova e, pensando nisso, o objetivo deste trabalho foi abordar o uso do bioestimulador de colágeno à base de ácido poli-l-láctico no tratamento da pele, procurando pontuar certas características da utilização em sua prática diária em consultório. A degradação do colágeno no organismo humano ocorre naturalmente a partir dos 30 anos de idade, com perda de aproximadamente 1% ao ano. Exposição solar excessiva, exercícios físicos intensos, poluição e tabagismo podem acelerar este processo. A aplicação de bioestimuladores promove a formação de novo colágeno, proporcionando recuperação da firmeza perdida ao longo dos anos e uma melhora na qualidade da pele.

Palavras-chave – Colágeno; Envelhecimento da pele; Rejuvenescimento; Ácido poli-l-láctico; Revisão da literatura.

ABSTRACT

Within the natural human aging process, our skin becomes thinner, drier and more fragile. Sagging, wrinkles and age spots begin to appear. Facial rejuvenation for destistry is a relatively new area of action and thinking about it, the objective of this work was to address the use of collagen biostimulator based on poly-l-lactic acid in the treatment of skin, seeking to highlight certain characteristics, in its use in your daily practice in the office. The degradation of collagen in the human body occurs naturally from the age of 30 with a loss of approximately 1% per year. Excessive sun exposure, intense physical exercise, pollution and smoking can accelerate this process. The application of biostimulators promotes the formation of new collagen providing recovery of the lost firmness over the years and an improvement in the quality of the skin.

Key words – Collagen; Skin aging; Rejuvenation; Poli-l-lactic acid; Literature review.

Referências

Gonçalves AP. Envelhecimento cutâneo cronológico. An Bras Dermatol 1991;66(5A):4-6.

Sharabi SE, Hatef DA, Koshy JC, Hollier Jr. LH, Yaremchuk MJ. Mechano transduction: the missing link in the facial aging puzzle? Aesthetic Plast Surg 2010;34(5):603-11.

Le Louarn C, Buthiau D, Buis J. Structural aging: the facial recurve concept. Aesthetic Plast Surg 2007;31(3):213-8.

Duracinsky M, Leclercq P, Herrmann S, Christen M-O, Dolivo M, Goujard C et al. Safety of poly-L-lactic acid (new-fill) in the treatment of facial lipoatrophy: a large observation study among HIV positive patients. BMC Infect Dis 2014:1:14-474.

Lam SM, Azizzadeh B, Graivier M. Injectable poly-L-lactic acid (Sculptra): technical considerations in soft-tissue contouring. Plast Reconstr Surg 2006;118(3):55-63.

Fitzgerald R, Vleggaar D. Facial volume restoration of the aging face with poly-l-lactic acid. Dermatol Ther 2011;24(1):2-27.

Bassichis B, Blick G, Conant M, Condoluci D, Echavez M, Eviatar J et al. Injectable poly-L-lactic acid for human immunodeficiency virus-associated facial lipoatrophy: cumulative year 2 interim analysis of an open-label study (FACES). Dermatol Surg 2012;38(7 Pt 2):1193-205.

Shermam RN. Sculptra: the new three-dimensional filler. Clin Plast Surg 2006;33(4):539-50.

Rhoda S, Narins MD. Minimizing adverse events associated with poly-l-lactic acid injection. Dermatol Surg 2008;34(suppl.1):S100-4.

Bauer U, Graivier MH. Optimizing injectable poly-L-lactic acid administration for soft tissue augmentation: the rationale for three treatment sessions. Can J Plast Surg 2011;19(3):22-7

Moyle GJ, Lysakova L, Brown S, Sibtain N, Healy J, Priest C et al. A randomized open-label study of immediate versus delayed polylactic acid injections for the cosmetic management of facial lipoatrophy in persons with HIV infection. HIV Med 2004;5(2):82-7.

Werschler WP, Weinkle S. Longevity of effects of injectable products for soft-tissue augmentation. J Drugs Dermatol 2005;4(1):20-7.

Narins RS. Minimizing adverse events associated with poly-L-lactic acid injection. Dermatol Surg 2008;34(suppl.1):S100-4.

Mazzuco R, Sadick NS. The use of poly-l-lactic acid in the gluteal area. Dermatol Surg 2016;42(3):441-3.

Moyle GJ, Brown S, Lysakova L, Barton SE. Long-term safety and efficacy of poly-L-lactic acid in the treatment of HIV-related facial lipoatrophy. HIV Med 2006;7(3):181-5.

Rohrich RJ, Pessa JE. The fat compartments of the face: anatomy and clinical implications for cosmetic surgery. Plast Reconstr Surg 2007;119(7):2219-27.

Engelhard P, Humble G, Mest D. Safety of Sculptra: a review of clinical trial data. Journal of Cosmetic and Laser Therapy 2005;7(3-4):201-5.

Alessio R, Rzany B, Eve L, Grangier Y, Herranz P, Olivier-Masveyraud F et al. European expert recommendations on the use of injectable poly-L-lactic acid for facial rejuvenation. J Drugs Dermatol 2014;13(9):1057-66.

Fitzgerald R. Advanced techniques for Sculptra. J Drugs Dermatol 2009;8(suppl.4):17-20.

Haneke E. Adverse effects of fillers and their histopathology. Facial Plast Surg 2014;30(6):599-614.

Palm MD, Woodhall KE, Butterwick KJ, Goldman MP. Cosmetic use of poly-l-lactic acid: a retrospective study of 130 patients. Dermatol Surg 2010;36(2):161-70.

Apikian M, Roberts S, Goodman GJ. Adverse reactions to polylactic acid injections in the periorbital area. J Cosmet Dermatol 2007;6(2):95-101.

Beer K, Avelar R. Relationship between delayed reactions to dermal fillers and biofilms: facts and considerations. Dermatol Surg 2014;40(11):1175-9.

Haneke E. Adverse effects of fillers and their histopathology. Facial Plast Surg 2014;30(6):599-614.

Parada MB, Michalany NS, Hassun KM, Bagatin E, Talarico S. A histologic study of adverse effects of different cosmetic skin fillers. Skinmed 2005;4(6):345-9.